Cyclization Thermostability Phytase - patented product,world leading



Habio cyclic thermostability phytase is a new kind of cyclic protein based on the protein self-splicing. The two ends of phytase were linked with the N-terminus and C-terminus of protein “intron” intein respectively to construct the expression vector of fusion gene. The fusion protein was induced to overproduction and cyclized by self-splicing of intein. Comparing with linear protein, the conformation changeability of cyclic protein is reduced and the enzyme is in an active state. As results, the stability and activity of cyclic phytase are much better. With no need of coating, Habio cyclization thermostability phytase can be released fast in gastro-intestinal tract of animals, biology efficiency is enhanced distinctly in the same time.

The N-terminus and C-terminus of cyclic protein was linked without any change of three-dimensional conformation (as following figure), thus kept the protein in active state.

 Cyclization Thermostability Phytase 

 To confirm the thermostability of Habio Cyclization Thermostability Phytase,Habio has done numbers of enzyme remaining rate test experiments under different temperature and humidity. The result is as follows:

         Remaining activity after processing 5min under 85% humidity and different temperture.



             Cyclization Thermostability Phytase

Remaining rate of different brands after processing 5min under 85% humidity and different temperture


              Cyclization Thermostability Phytase


Superior quality

1,Higher thermostablity and higher remaining rate after feed granulating compared with other similar products.

2,there is no change on the three-dimensional conformation of Habio cyclic thermostability phytase;  Protein will not lose activity, having more stable performance. Higher biological efficiency could be achieved by combining and decomposing substrates more effectively and no need to release in animals’ the gastrointestinal tract because of no more coating.

3,Habio Cyclization Thermostability Phytase can not only improve the stability, but also improve the biological value of phytase. .




 Dosage in complete feed (g/t) 

 Phytase activity in complete feed 


Pigs feed




After premixing

Poultry feed 



Notes: the Specific amount is determined by feed ingredients, processing conditions, expectations of the effectiveness and feed cost.



FOB Price: 1-50 USD/Kg
Minimum Order: 500Kg
Port: Shanghai/Qingdao port etc.
Payment Terms: L/C,D/A,D/P,T/T,Western Union,MoneyGram

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